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General software || Protein related || Nucleotide related || Molecular evolution || Protein residue network || Antiviral drug design || Antibody database

 

 

 

 

 

 

 

 


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Gblocks
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Select conservative blocks from multiple alignments for phylogenetic analysis

Gblocks (Linux, windows and web version)

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DAMBE
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Nucleotide substitution saturation detection

There are certain prerequisites for building a tree, for example: for nucleotide sequences, the most important one is the test of substitution saturation. If the sequence used to build a tree has become saturated, there is no need to build a tree.
DAMBE is a tool used for saturation testing.

DAMBE (windows,Linux versions)

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Asatura
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Amino acid saturation test

Asatura.rar 0.2MB (Fangluan Gao)

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jModelTest
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Nucleotide substitution model selection

jmodeltest-2.1.7-win.tar.gz (9.2MB

jModelTest v2.1.10

jModelTest 2.1.10 Full release (tar.gz)

jModelTest 2.1.10 Manual (pdf)

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ModelTest-NG
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ModelTest-NG: A New and Scalable Tool for the Selection of ...

ModelTest-NG

 

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ModelFinder
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ModelFinder

 

 

 

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modelgenerator
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Nucleotide and amino acid substitution model selection tools

modelgenerator_v_851.zip0.8MB (Fangluan Gao)

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modeltest
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Nucleotide model selection (48 methods)
modeltest3.7.zip0.9MB

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MrModeltest
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Nucleotide model selection (24 types)
MrModeltest2.3.zip0.5MB

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MrMTgui
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Evolutionary model selection tool

It integrates PAUP, modeltest and MrModeltest into a graphical tool.

mrmtgui.zip 4.6MB (Fangluan Gao)

Use diagrams to explain the selection of nucleotide substitution models – using MrMTgui

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PAUP
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PAUP 4.0 4.0b10 S[ecial Version

paupwin32_4b.rar1.3MB
PAUP4Registered version (Classic)

PAUP instructions

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MEGA-X
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MEGA-X

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RAxML
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RAxML || RAxML v8.2.X Manual

RAxML version 8

Using RAxML to build a maximum likelihood evolution tree (in Chinese)

Constructing Phylogenetic Tree with Online RaxML ( in Chinese)

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BEAST2
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BEAST2 || online manual of BEAST2

Tutorials (see this)

Differentiation time analysis—beast2 software introduction (in Chinese)

Analysis of differentiation time based on beast2 software (in Chinese)

Introduction to BEAST2

BEAST Analisys FAQ (in Chinese)

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FigTree
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FigTree || Constructing a columnar evolutionary tree with FigTree ( in Chinese)

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TempEst
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TempEst || TempEst paper

RDP4 | Instruction | RDP4 Instruction Manual

Evolview ||Beautify the evolution tree with evolview (in Chinese)

Using Evolview to beautify the evolution tree tutorial and how to use it (Chinese)

advanced use of Evolview (in Chinese)

PhyML 3.0 || Mesquite

DnaSP ||

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IQ-TREE
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Documentation

IQ-TREE Tutorials and Manual in one PDF

IQ-TREE的使用 - 超快速用极大似然法构建进化树

使用IQ-TREE构建系统进化树

新一代建树工具IQ-Tree介绍

基于ML法重建系统发育树-IQ-TREE篇

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SimPlot
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Graphical analysis and analysis of genetic recombination tutorial (Simplot) ( in Chinese)

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Arlequin

Free Phylogenetic Network Software

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TimeTree
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TimeTree || Original article

 

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PAML
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paml

PAML Manual (pamlDOC.pdf) || || PAML FAQs (pamlFAQs.pdf)

PAML一般使用操作 || || PAML中文手册 || || PAML-中文说明

PAML中文手册

 

比较基因组分析之正选择分析(dN/dS或ka/ks计算原理) (video)

 

 

Gao Fangluan's blog

   
Selection of nucleotide substitution model  
selection of nucleotide substitution models-Using jModelTest  
   

Our Focus

We take S protein as the research focus and take coronavirus recombination as the exploration direction.

 

 

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